Alternative Approaches to Molecular Biology | MIT 7.01SC Fundamentals of Biology
Alternative Approaches to Molecular Biology Instructor: Eric Lander View the complete course: http://ocw.mit.edu/7-01SCF11 License: Creative Commons ...
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ERIC LANDER: So, now what I'd like to do is turn to variations on the theme. One of the best ways to understand what's going on with DNA goes to RNA goes to protein is to consider how it works in different organisms. And the organisms we'll consider are eukaryotes, like you; prokaryotes, like a bacterium; and viruses. And each does the same basic copying of nucleic acid to nucleic acid, transcription, and translation. But there are some pretty fascinating variations on the theme. So let's turn to those variations. Let's start with DNA replication. For eukaryotes, your genome are long, double-stranded DNA molecules, and they're linear. Long, linear, double stranded-- ds for double. I'll write it out-- double stranded DNA. You know this. And you've g...
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ERIC LANDER: So, now what I'd like to do is turn to variations on the theme. One of the best ways to understand what's going on with DNA goes to RNA goes to protein is to consider how it works in different organisms. And the organisms we'll consider are eukaryotes, like you; prokaryotes, like a bacterium; and viruses. And each does the same basic copying of nucleic acid to nucleic acid, transcription, and translation. But there are some pretty fascinating variations on the theme. So let's turn to those variations. Let's start with DNA replication. For eukaryotes, your genome are long, double-stranded DNA molecules, and they're linear. Long, linear, double stranded-- ds for double. I'll write it out-- double stranded DNA. You know this. And you've g...
